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Publicações

*indica o autor para correspondência e #indica iguais contribuições dos autores

Publicações Destacadas

Orea-Soufi A, Paik J, Bragança J, Donlon TA, Bradley J, Willcox BJ and Link W – FOXO transcription factors as therapeutic targets in human diseases – Trends in Pharmacological Sciences – in press October 2022    https://doi.org/10.1016/j.tips.2022.09.010

 

Heidari MM, Manshadi SAM, Eshghi AR, Talebi F, Khatami M, Bragança J, Ordooei M, Chamani R and Ghasemi F – Mutational and bioinformatics analysis of the NKX2.1 gene in a cohort of Iranian pediatric patients with congenital hypothyroidism (CH) - Physiology International – published online 7 June 2022 

 

Malho Guedes A, Calças Marques R, Ribeiro B, Fernandes MT, Faísca M, Silva AP, Bragança J,  Rodrigues A – Peritoneal protein loss, inflammation and nutrition: refuting myths – Front. Med. (2022) 9, Article 884061.

Bragança J*, Figueiredo S, Rego CA, dos Reis Conceição F, Neves de Jesus S – UALGORITMO, a new instrument of the University of Algarve for scientific outreachBioChem (2022) 2, 93-103.

Fernandes MT, Yassuda V, Bragança J, Link W, Ferreira BI, De Sousa-Coelho Al – Tribbles gene expression profiles in colorectal cancer – Gastrointest. Disord. (2021) 3, 218-236.

Calado SM, Bento D, Marques N and Bragança J* – Generation and cardiac differentiation of a human induced pluripotent stem cell line UALGi002-A from a female patient with Left-Ventricular Noncompaction CardiomyopathyStem Cell Res. (2021), 55, 102462.

 

Calado SM, Bento D, Justino D, Mendes-Silva L, Marques N and Bragança J* – Generation of a human induced pluripotent stem cell line (UALGi001-A) from a patient with Left-Ventricular Noncompaction Cardiomyopathy – Stem Cell Res. (2021) 53, 102302.

Fernandes MT, Calado SM, Mendes-Silva L and Bragança J* – CITED2 and the modulation of the hypoxic response in cancer – World J. Clin. Oncol. (2020) 11, 260-274.

 

Matias AC, Dias J, Barata M, Araújo RL, Bragança J and Pousão-Ferreira P – Taurine modulates protein turnover in several tissues of meagre juveniles – Aquaculture (2020) 735478.

Duarte AJ, Ribeiro D, Santos R, Moreira L, Bragança J and Amaral O – Induced pluripotent stem cell line (INSAi002-A) from a Fabry Disease patient hemizygote for the rare p.W287X mutation - Stem Cell Res. (2020) 45, 101794   

Duarte AJ, Ribeiro D, Santos R, Quint M, Moreira L, Bragança J and Amaral  – Induced pluripotent stem cell line (INSAi001-A) from a Gaucher Disease type 3 patient compound heterozygote for mutations in the GBA1 gene – Stem Cell Res. (2019) 41, 101595 

 

Santos JMA, Mendes-Silva L, Afonso V, Martins G, Machado RSR, Lopes JA, Cancela L, Futschik ME, Sachinidis A, Gavaia P and Bragança J* - Exogenous Wnt5a and Wnt11 proteins rescue Cited2 dysfunction in mouse embryonic stem cells and zebrafish morphants – Cell Death & Disease (2019), 10, 582.

Bragança J*, Mendes-Silva L, Lopes JA, and Calado SM - CITED Proteins in the Heart of Pluripotent Cells and in Heart’s Full Potential - Regen. Med. Front. 2019;1:e190005. https://doi.org/10.20900/rmf20190005

 

Bragança J*, Lopes JA, Mendes-Silva L and Santos JMA - Induced pluripotent stem cells, a giant leap for mankind therapeutic applications - World J. Stem Cells (2019) 11, 421-430.

 

Bragança J - SMAD2/3, versatile molecular tools for cellular engineering - Stem Cell Investig., (2018) 5, 24 - Comentário Editorial

 

Pinto J, Machado R, Magno R, Oliveira D, Machado S, Andrade R, Bragança J, Duarte I and Futschik M – StemMapper: A Curated Gene Expression Database for Stem Cell Lineage Analysis Nucleic Acids Res. (2018) 6(D1):D788-D793.

Charneca J#, Matias AC#, Escapa AL, Fernandes C, Alves A, Santos JMA, Nascimento R and Bragança J* - Ectopic expression of CITED2 prior to reprogramming, promotes and homogenises the conversion of somatic cells into induced pluripotent stem cells -  Exp. Cell Res. (2017) 359, 290-300.

Santos T, Ferreira R, Quartin E, Boto C, Saraiva C, Bragança J, Peça J, Rodrigues C, Ferreira L and Bernardino L – Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles – Acta Biomaterialia (2017) 59, 293-302.

 

Inácio P, Medeiros MCR, Mestre A, Asgarif S, Canudo J, Santos JMA, Bragança J, Biscarini F and Gomes HL – Bioelectrical signal detection using conducting polymer electrodes and the displacement current method – IEEE Sensors Journal (2017) 17, 3961-3966.

 

Medeiros MCR, Mestre AGL, Inácio PMC, Santos JMA, Araújo IM, Bragança J, Biscarini F and Gomes HL – Performance assessment of polymer based electrodes for in vitro electrophysiological sensing: the role of the electrode impedance – Proc. SPIE (2016) 9944 - Organic Sensors and Bioelectronics IX, 994404 doi:10.1117/12.2237659

Pacheco-Leyva I, Matias AC#, Oliveira DV#, Santos JMA#, Nascimento R, Guerreiro E, Michell AC, van De Vrugt AM, Machado-Oliveira G, Ferreira G, Domian I and Bragança J* - Cited2 cooperates with Isl1 and promotes cardiac differentiation of mouse embryonic stem cells – Stem Cell Reports (2016) 7, 1037–1049.

 

Machado-Oliveira G, Guerreiro E, Matias AC, Facucho-Oliveira J, Pacheco-Leyva I and Bragança J* - FBXL5 modulates HIF-1α transcriptional activity by degradation of CITED2Arch. Biochem. Biophys. (2015) 576, 61-72. 

Kranc KR, Oliveira DV, Armesilla-Diaz A, Pacheco-Leyva I, Matias AC,  Escapa AL,  Subramani C, Wheadon H, Trindade M, Nichols J, Kaji K, Enver T and Bragança J*Acute loss of Cited2 impairs Nanog expression and decreases self-renewal of mouse embryonic stem cellsStem Cells (2015) 33, 699-712.

Bragança J* and Santos JMAIs CITED2 a general regulator of stem cell functions?Stem Cell Transl. Invest. (2015) 2:e755.

 

Simões B, Conceição N, Matias AC, Bragança J, Kelsh RN and Cancela ML – Molecular characterization of Cbfβ gene and identification of new transcription variants: Implications for functionArch. Biochem. Biophys. (2015) 567, 1-12.

 

Pinto JP, Kalathur RKR, Machado RSR, Xavier JM, Bragança J and Futschik ME – StemCellNet: an interactive platform for network-oriented investigations in stem cell biology - Nucleic Acids Res. (2014) 42 (Web Server issue), W154-160.

 

Xapelli S, Agasse F, Sardà-Arroyo L, Bernardino L, Santos T, Ribeiro FF, Valero J, Bragança J, Schitine C, de Melo Reis RA, Sebastião AM and Malva JO - Activation of type I cannabinoid  receptor (CBR1) promotes neurogenesis in murin subventricular zone cell culturesPLoS ONE (2013) 21, e63529.

 

Agasse F, Xapelli S, Coronas V,  Christiansen SH, Rosa AI, Sardà-Arroyo L, Santos T,  Ferreira R,  Schitine C, Harnois T, Bourmeyster N, Bragança J, Bernardino L, Malva JO and Woldbye DPD - Galanin promotes neuronal differentiation in murine subventricular zone cell culturesStem Cells and Dev. (2013) 21, 1693-1708.

MacDonald ST, Bamforth SD, Bragança J, Chen C-M, Broadbent C, Schneider JE, Schwartz RJ and Bhattacharya S – A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular developmentEur. Heart J.  (2013) 34, 2557-2565.

 

Santos T, Ferreira R, Maia J, Agasse F, Xapelli S, Cortes L, Bragança J, Malva J, Ferreira L and Bernardino L – Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brainACS Nano (2012) 6, 10463-10474.

 

Chen C, Bentham J, Cosgrove C, Braganca J, Cuenda A, Bamforth SD, Schneider JE, Watkins H, Keavney B, Davies B and Bhattacharya S – Functional Significance of SRJ Domain Mutations in CITED2 - PLoS ONE (2012) 7, e46256.

 

Bernardino L, Eiriz MF, SantosT, Xapelli S, Grade S, Rosa AI, Cortes L, Ferreira R, Bragança J, Agasse F, Ferreira L and Malva JO – Histamine Stimulates Neurogenesis in the Rodent Subventricular ZoneStem Cells (2012) 30, 773-784.

Michell AC, Bragança J, Broadbent C, Joyce B, Franklyn A, Schneider JE, Bhattacharya S and Bamforth SD - A novel role for transcription factor Lmo4 in thymus development through genetic interaction with Cited2Dev. Dyn. (2010) 239, 1988-1994.

 

Stevens J, Ermakov A, Bragança J, Hilton H, Underhill P, Bhattacharya S, Brown NA and Norris DP – Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flowBMC Dev. Biol. (2010) 10, 54. 

 

Woon PY#, Kaisaki PJ#, Bragança J, Bihoreau M-T, Levy JC, Farrall M and Gauguier D - Aryl hydrocarbon receptor nuclear translocator-like protein (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes - Proc. Natl. Acad. Sci. USA (2007) 104, 14412-14417.

 

Fox SB, Bragança J, Turley H, Campo L, Han C, Gatter KC, Bhattacharya S and Harris AL - CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia inducible factor 1α - Cancer Res. (2004) 64, 6075–6081.

Bamforth SD#, Bragança J#, Farthing CR#, Schneider JE, Broadbent C, Clarke K, Neubauer S, Brown NA, Anderson RH and Bhattacharya S - Cited2 controls left-right patterning and heart development through a Nodal–Pitx2c pathway - Nature Genet. (2004) 36, 1189-1196.

 

Kranc RK, Bamforth SD, Bragança J, Norbury C, van Lohuizen M and Bhattacharya S - Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF - Mol. Cell Biol. (2003) 23, 7658-7666.

Bragança J, Eloranta JJ, Bamforth SD, Ibbit JC, Hurst HC and Bhattacharya S - Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2 - J. Biol. Chem.  (2003) 278, 16021-16029.

Bragança J, Swingler T,  Marques FIR, Jones T, Eloranta JJ, Hurst HC, Shioda T and Bhattacharya S - Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2 - J. Biol. Chem. (2002)  277, 8559-8565.

 

Yahata T, Takedatsu H, Dunwoodie SL, Bragança J, Swingler T, Hur J, Coser KR, Isselbacher KJ, Bhattacharya S and Shioda T - Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells - Genomics (2002) 80, 601-613.

 

Morin P#, Bragança J#, Bandu M-T, Lin R, Hiscott J, Doly J and Civas A - Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-a gene transcription - J. Mol. Biol. (2002) 316, 1009-1022.

Bamforth SD#, Bragança J#, Eloranta JJ, Murdoch JN, Marques FIR, Kranc RK, Farza H, Henderson DJ, Hurst HC and  Bhattacharya S -  Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator - Nature Genet. (2001) 29, 469-474.

 

Bragança J and Civas A - Type I interferon gene expression: Differential expression of IFN-A genes induced by viruses and double-stranded RNA - Biochimie  (1998) 80, 673-687.

 

Bragança J, Génin P, Bandu M-T, Darracq N, Vignal M, Cassé C, Doly J and Civas A - Synergism between multiple virus-induced factor-binding elements involved in the differential expression of IFN-A genes - J. Biol. Chem. (1997) 272, 22154-22162.

 

Génin P, Bragança J, Darracq N, Doly J and Civas A - A novel PRDI and TG-binding activity involved in the virus-induced transcription of the IFN-A genes - Nucleic Acids Res. (1995) 23, 5055-5063.

Capítulos de Livros

Amaral O, Duarte A, Ribeiro D, Santos R, Bragança J - Applications of iPSCs in Gaucher disease and other rare sphingolipidose – Chapter 8 in iPSCs - State of the Science (Elsevier Inc.), por convite de Alexander Birbrair (Editor) – (2022) volume 16 eBook ISBN: 978-0-323-85645-4

 

Bragança J*, Machado-Oliveira G, Pacheco-Leyva I, Matias AC – Understanding cancer stem cells biology to get rid of tumours – International Manual of Oncology Practice. (iMOP) - Principles of Medical Oncology. 2ND EDITION de Mello RA, Tavares Á, Mountzios G (Eds.). Springer International Publishing. 2019. Chapter 2, p15-28. ISBN 978-3-030-16245-0. Hardcover ISBN 978-3-030-16244-3   

 

Asgarifar S, Gomes HL, Mestre A, Inácio P, Bragança J, Borme J, Machado Jr G, Cerqueira F and Alpuim P – Electrochemically Gated Graphene Field-Effect Transistor for Extracellular Cell Signal Recording - Technological Innovation for Cyber-Physical Systems. Camarinha-Matos LM , Falcão AM, Vafaei N, Najdi N (Eds.). Springer International Publishing 2016. Volume 470 of the series IFIP Advances in Information and Communication Technology, p 558-564. eBook ISBN: 978-3-319-31165-4. Hard cover: ISBN 978-3-319-31164-7

 

Bragança J*, Machado-Oliveira G, Pacheco-Leyva I, Matias ACUnderstanding cancer stem cells biology to get rid of tumours – International Manual of Oncology Practice. (iMOP) - Principles of Medical Oncology. de Mello RA, Tavares Á, Mountzios G (Eds.). Springer International Publishing. 2015. eBook ISBN: 978-3-319-21683-6. Hardcover ISBN 978-3-319-21682-9

Bragança J and Bhattacharya S - Two-hybrid systems - In: Creighton T. ed. Encyclopaedia of Molecular Medicine. John Wiley, New York (2002).

 

 

 

 

Publicações em Revistas Portuguesas com Revisão por Pares

Matias AC, Pacheco-Leyva I, Machado-Oliveira G, Oliveira DV and Bragança J* – Células estaminais pluripotentes induzidas – elenco promissor para o futuro da medicinaBoletim de Biotecnologia (2013) 4, 34-36. 

 

Bragança J*, Tavares A and Belo JA – Células estaminais e medicina regenerativa – um admirável mundo novoCanal BQ (2010) 7, 4-17.

 

Correia R and Bragança J* – Células estaminais adultas em medicinaCanal BQ (2010) 7, 18-23. 

Publicações em Português/Inglês para divulgação da ciência  ao público

Silva-Mendes L and Bragança J*Prevention of congenital heart anomalies: the secret kept by embryonic stem cellsATLAS OF SCIENCE (2021) 8 March.

 

Bragança J* and Silva-Mendes L – Os poderes secretos das  células estaminais para limitar as malformações do coração  UALGORITMO (2020) 2, 39-43. 

 

Bragança J* and Santos JMA Rejuvenescer células "velhas" é possivél? – UALGORITMO (2019) 1, 17-22. 

Coordenador e Editor do                              revista em Português para divulgação da ciência
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