STEM CELLS
BIOLOGY LAB
José Bragança
Our group is interested in genes and regulatory pathways that control pluripotent stem cells (ESC - Embryonic Stem Cells/iPSC - induced pluripotent Stem cells) self-renewal and differentiation. The long-term aim of our work is to understand the molecular mechanisms involved in pluripotency and differentiation processes occurring in mouse and human cells in order to achieve cell-types specification in vitro for therapeutic purposes, and understand mechanisms of diseases.
GROUP MEMBERS
NEWS
We are recruiting a fellow (grant equivalent to that proposed by FCT/Bolsas de Investigação BI), in the field of embryonic heart development and of mechanisms of human congenital heart diseases using iPSC (induced Pluripotent Stem Cells) and other models.
The contract will have a maximum duration of 2 years, and the work will be carried out at the ABC-RI https://abcri.pt/research-groups/jose-braganca/.
DEADLINE: 31st of January 2023.
MORE INFORMATION ABOUT THE JOB AND THE APPLICATION HERE:
https://euraxess.ec.europa.eu/jobs/57903#where-to-apply
PUBLICATIONS
RECENT PUBLICATIONS
Heidari MM, Khatami M, Kamalipour A, Kalantari M, Movahed M, Emmamy MH, Hadadzade M, Bragança J, Namnabat M, Mazrouei B - “Mitochondrial Mutations in Protein Coding Genes of Respiratory Chain including Complexes IV, V, and mt-tRNA genes are Associated Risk Factors for Congenital Heart Disease” - EXCLI Journal (2022) 2, 1306-1330.
Orea-Soufi A, Paik J, Bragança J, Donlon TA, Bradley J, Willcox BJ and Link W – “FOXO transcription factors as therapeutic targets in human diseases” – Trends in Pharmacological Sciences (2022) 43, 1070-1084.
Malho Guedes A, Calças Marques R, Ribeiro B, Fernandes MT, Faísca M, Silva AP, Bragança J, Rodrigues A – “Peritoneal protein loss, inflammation and nutrition: refuting myths” – Front. Med. (2022) 9, Article 884061.