Our group is interested in genes and regulatory pathways that control pluripotent stem cells (ESC - Embryonic Stem Cells/iPSC - induced pluripotent Stem cells) self-renewal and differentiation. The long-term aim of our work is to understand the molecular mechanisms involved in pluripotency and differentiation processes occurring in mouse and human cells in order to achieve cell-types specification in vitro for therapeutic purposes, and understand mechanisms of diseases.
José Bragança receives the award of best Professor of the Faculty of Medicine and Biomedical Sciences 2020 based on students enquiry!
Amaral O, Duarte A, Ribeiro D, Santos R, Bragança J - “Applications of iPSCs in Gaucher disease and other rare sphingolipidose” – Chapter 8 in iPSCs - State of the Science (Elsevier Inc.), por convite de Alexander Birbrair (Editor) – (2022) volume 16 eBook ISBN: 978-0-323-85645-4
Fernandes MT, Yassuda V, Bragança J, Link W, Ferreira BI, De Sousa-Coelho Al – “Tribbles gene expression profiles in colorectal cancer” - Gastrointest. Disord. (2021) 3, 218-236.
Calado SM, Bento D, Marques N and Bragança J - “Generation and cardiac differentiation of a human induced pluripotent stem cell line UALGi002-A from a female patient with Left-Ventricular Noncompaction Cardiomyopathy” - Stem Cell Res. (2021), 55, 102462.