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STEM CELLS
BIOLOGY LAB
 
 
 

 

 
José Bragança

RESEARCH

Our group is interested in genes and regulatory pathways that control pluripotent stem cells (ESC - Embryonic Stem Cells/iPSC - induced pluripotent Stem cells) self-renewal and differentiation. The long-term aim of our work is to understand the molecular mechanisms involved in pluripotency and differentiation processes occurring in mouse and human cells in order to achieve cell-types specification in vitro for therapeutic purposes, and understand mechanisms of diseases.

GROUP MEMBERS
NEWS
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PUBLICATIONS

RECENT PUBLICATIONS

Bragança J, Pinto R, Silva B, Marques N, Leitão HS, Fernandes MT Charting the path: navigating embryonic development to potentially safeguard against congenital heart defectsJ. Pers. Med. (2023), 13, 1263.

Esteves F, Brito D, Rajado AT, Silva N, Apolónio J, Roberto VP, Araújo IM, Nóbrega C, Castelo-Branco P, Bragança J and ALFAScore Consortium – Reprogramming iPSCs to study age-related diseases: models, therapeutics, and clinical trials – Mech. Ageing  Dev. (2023) 214, 111854.

 

Correia CD, Ferreira A, Fernandes MT, Silva BM, Esteves F, Leitão HL, Bragança J and Calado SM - Human Stem Cells for cardiac disease modeling and (pre)clinical applications – are we on the road to success? – Cells (2023), 12, 1727.

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