Brito D, Esteves F, Rajado AT, Silva N, Alfa Score Consortium, Araújo I, Bragança J, Castelo-Branco P and Nóbrega C – Assessing cognitive decline in the aging brain: lessons from animal and human studies – npg Aging (2023) 9, 23.

 

Bragança J*, Pinto R, Silva B, Marques N, Leitão HS, Fernandes MT – Charting the path: navigating embryonic development to potentially safeguard against congenital heart defects – J. Pers. Med. (2023), 13, 1263.

 

Esteves F, Brito D, Rajado AT, Silva N, Apolónio J, Roberto VP, Araújo IM, Nóbrega C, Castelo-Branco P, Bragança J* and ALFAScore Consortium – Reprogramming iPSCs to study age-related diseases: models, therapeutics, and clinical trials – Mech. Ageing  Dev. (2023) 214, 111854. 

​

García-Ortega MB, Aparicio E, Griñán-Lisón C, Jiménez G, López-Ruiz E, Palacios JL, Ruiz-Alcalá G, Alba C, Martínez A, Boulaiz H, Perán M, Hackenberg M, Bragança J, Calado SM, Marchal JA and García Chaves MA – Interferon-alpha decreases cancer stem cell properties and modulates exosomes in Malignant Melanoma – Cancers (2023), 15, 3666. 

 

Correia CD, Ferreira A, Fernandes MT, Silva BM, Esteves F, Leitão HL, Bragança J and Calado SM - Human Stem Cells for cardiac disease modeling and (pre)clinical applications – are we on the road to success? – Cells (2023), 12, 1727.

 

Silva N, Rajado AT, Esteves F, Brito D, Apolónio J, Roberto VP, Binnie A, ALFAScore Consortium, Araújo IM, Nóbrega C, Bragança J and Castelo-Branco P – Measuring healthy ageing – Current and future tools – Biogerontology (2023), https://doi.org/10.1007/s10522-023-10041-2

 

Rajado AT, Silva N, Esteves F, Brito D, ALFA Score Consortium, Binnie A, Araújo IM, Nóbrega C, Bragança J and Castelo-Branco P - How can we modulate aging through nutrition and physical exercise? An epigenetic approach – Aging (Albany NY) (2023) 15, 3191-321.

​

Heidari MM, Khatami M, Kamalipour A, Kalantari M, Movahed M, Emmamy MH, Hadadzade M, Bragança J, Namnabat M, Mazrouei B - Mitochondrial Mutations in Protein Coding Genes of Respiratory Chain including Complexes IV, V, and mt-tRNA genes are Associated Risk Factors for Congenital Heart Disease – EXCLI Journal (2022) 2, 1306-1330.

 

Orea-Soufi A, Paik J, Bragança J, Donlon TA, Bradley J, Willcox BJ and Link W – FOXO transcription factors as therapeutic targets in human diseases – Trends in Pharmacol. Sci. (2022) 43, 1070-1084.

​

Heidari MM, Manshadi SAM, Eshghi AR, Talebi F, Khatami M, Bragança J, Ordooei M, Chamani R and Ghasemi F – Mutational and bioinformatics analysis of the NKX2.1 gene in a cohort of Iranian pediatric patients with congenital hypothyroidism (CH) - Physiology International (2022) 109, 261-277.

​

Malho Guedes A, Calças Marques R, Ribeiro B, Fernandes MT, Faísca M, Silva AP, Bragança J, Rodrigues A – Peritoneal protein loss, inflammation and nutrition: refuting myths – Front. Med. (2022) 9, Article 884061.

 

Bragança J*, Figueiredo S, Rego CA, dos Reis Conceição F, Neves de Jesus S – UALGORITMO, a new instrument of the University of Algarve for scientific outreach – BioChem (2022) 2, 93-103.

​

Fernandes MT, Yassuda V, Bragança J, Link W, Ferreira BI, De Sousa-Coelho Al – Tribbles gene expression profiles in colorectal cancer –Gastrointest. Disord. (2021) 3, 218-236.

​

Calado SM, Bento D, Marques N and Bragança J* – Generation and cardiac differentiation of a human induced pluripotent stem cell line UALGi002-A from a female patient with Left-Ventricular Noncompaction Cardiomyopathy – Stem Cell Res. (2021), 55, 102462.

 

Calado SM, Bento D, Justino D, Mendes-Silva L, Marques N and Bragança J* – Generation of a human induced pluripotent stem cell line (UALGi001-A) from a patient with Left-Ventricular Noncompaction Cardiomyopathy – Stem Cell Res. (2021) 53, 102302.

​

Fernandes MT, Calado SM, Mendes-Silva L and Bragança J* – CITED2 and the modulation of the hypoxic response in cancer – World J. Clin. Oncol. (2020) 11, 260-274.

​

Matias AC, Dias J, Barata M, Araújo RL, Bragança J and Pousão-Ferreira P – Taurine modulates protein turnover in several tissues of meagre juveniles – Aquaculture (2020) 735478.

​

Duarte AJ, Ribeiro D, Santos R, Moreira L, Bragança J and Amaral O – Induced pluripotent stem cell line (INSAi002-A) from a Fabry Disease patient hemizygote for the rare p.W287X mutation - Stem Cell Res. (2020) 45, 101794  

​

Duarte AJ, Ribeiro D, Santos R, Quint M, Moreira L, Bragança J and Amaral O – Induced pluripotent stem cell line (INSAi001-A) from a Gaucher Disease type 3 patient compound heterozygote for mutations in the GBA1 gene – Stem Cell Res. (2019)  41, 101595

 

Santos JMA, Mendes-Silva L, Afonso V, Martins G, Machado RSR, Lopes JA, Cancela L, Futschik ME, Sachinidis A, Gavaia P and Bragança J* - Exogenous Wnt5a and Wnt11 proteins rescue Cited2 dysfunction in mouse embryonic stem cells and zebrafish morphants – Cell Death & Disease (2019), 10, 582.

​

Bragança J*, Mendes-Silva L, Lopes JA, and Calado SM - CITED Proteins in the Heart of Pluripotent Cells and in Heart’s Full Potential - Regen. Med. Front. 2019;1:e190005. https://doi.org/10.20900/rmf20190005

​

Bragança J*, Lopes JA, Mendes-Silva L and Santos JMA - Induced pluripotent stem cells, a giant leap for mankind therapeutic applications - World J. Stem Cells (2019) 11, 421-430.

​

Bragança J - SMAD2/3, versatile molecular tools for cellular engineering - Stem Cell Investig. (2018) 5, 24 - Editorial comment

 

Pinto J, Machado R, Magno R, Oliveira D, Machado S, Andrade R, Bragança J, Duarte I and Futschik M – StemMapper: A Curated Gene Expression Database for Stem Cell Lineage Analysis – Nucleic Acids Res. (2018) 6(D1):D788-D793.

​

Charneca J#, Matias AC#, Escapa AL, Fernandes C, Alves A, Santos JMA, Nascimento R and Bragança J* - Ectopic expression of CITED2 prior to reprogramming, promotes and homogenises the conversion of somatic cells into induced pluripotent stem cells -  Exp. Cell Res. (2017) 359, 290-300.

​

Santos T, Ferreira R, Quartin E, Boto C, Saraiva C, Bragança J, Peça J, Rodrigues C, Ferreira L and Bernardino L – Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles – Acta Biomaterialia (2017) 59, 293-302.

​

Inácio P, Medeiros MCR, Mestre A, Asgarif S, Canudo J, Santos JMA, Bragança J, Biscarini F and Gomes HL – Bioelectrical signal detection using conducting polymer electrodes and the displacement current method –  IEEE Sensors Journal (2017) 17, 3961-3966.

 

Medeiros MCR, Mestre AGL, Inácio PMC, Santos JMA, Araújo IM, Bragança J, Biscarini F and Gomes HL – Performance assessment of polymer based electrodes for in vitro electrophysiological sensing: the role of the electrode impedance – Proc. SPIE (2016) 9944 - Organic Sensors and Bioelectronics IX, 994404 doi:10.1117/12.2237659

​

Pacheco-Leyva I, Matias AC#, Oliveira DV#, Santos JMA#, Nascimento R, Guerreiro E, Michell AC, van De Vrugt AM, Machado-Oliveira G, Ferreira G, Domian I and Bragança J* - Cited2 cooperates with Isl1 and promotes cardiac differentiation of mouse embryonic stem cells – Stem Cell Reports (2016) 7, 1037–1049.

​

Machado-Oliveira G, Guerreiro E, Matias AC, Facucho-Oliveira J, Pacheco-Leyva I and Bragança J* - FBXL5 modulates HIF-1α transcriptional activity by degradation of CITED2 – Arch. Biochem. Biophys. (2015) 576, 61-72. 

 

Kranc KR, Oliveira DV, Armesilla-Diaz A, Pacheco-Leyva I, Matias AC,  Escapa AL,  Subramani C, Wheadon H, Trindade M, Nichols J, Kaji K, Enver T and Bragança J* – Acute loss of Cited2 impairs Nanog expression and decreases self-renewal of mouse embryonic stem cells – Stem Cells (2015) 33, 699-712.

 

Bragança J* and Santos JMA – Is CITED2 a general regulator of stem cell functions? – Stem Cell Transl. Invest. (2015) 2:e755.

 

Simões B, Conceição N, Matias AC, Bragança J, Kelsh RN and Cancela ML – Molecular characterization of Cbfβ gene and identification of new transcription variants: Implications for function – Arch. Biochem. Biophys. (2015) 567, 1-12.

 

Pinto JP, Kalathur RKR, Machado RSR, Xavier JM, Bragança J and Futschik ME – StemCellNet: an interactive platform for network-oriented investigations in stem cell biology - Nucleic Acids Res. (2014) 42 (Web Server issue), W154-160.

 

Xapelli S, Agasse F, Sardà-Arroyo L, Bernardino L, Santos T, Ribeiro FF, Valero J, Bragança J, Schitine C, de Melo Reis RA, Sebastião AM and Malva JO - Activation of type I cannabinoid  receptor (CBR1) promotes neurogenesis in murin subventricular zone cell cultures – PLoS ONE (2013) 21, e63529.

 

Agasse F, Xapelli S, Coronas V,  Christiansen SH, Rosa AI, Sardà-Arroyo L, Santos T,  Ferreira R,  Schitine C, Harnois T, Bourmeyster N, Bragança J, Bernardino L, Malva JO and Woldbye DPD - Galanin promotes neuronal differentiation in murine subventricular zone cell cultures – Stem Cells and Dev. (2013) 21, 1693-1708.

​

MacDonald ST, Bamforth SD, Bragança J, Chen C-M, Broadbent C, Schneider JE, Schwartz RJ and Bhattacharya S – A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development – Eur. Heart J.  (2013) 34, 2557-2565.

 

Santos T, Ferreira R, Maia J, Agasse F, Xapelli S, Cortes L, Bragança J, Malva J, Ferreira L and Bernardino L – Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain – ACS Nano (2012) 6, 10463-10474.

 

Chen C, Bentham J, Cosgrove C, Braganca J, Cuenda A, Bamforth SD, Schneider JE, Watkins H, Keavney B, Davies B and Bhattacharya S – Functional Significance of SRJ Domain Mutations in CITED2 - PLoS ONE (2012) 7, e46256.

 

Bernardino L, Eiriz MF, SantosT, Xapelli S, Grade S, Rosa AI, Cortes L, Ferreira R, Bragança J, Agasse F, Ferreira L and Malva JO – Histamine Stimulates Neurogenesis in the Rodent Subventricular Zone – Stem Cells (2012) 30, 773-784.

​

Michell AC, Bragança J, Broadbent C, Joyce B, Franklyn A, Schneider JE, Bhattacharya S and Bamforth SD - A novel role for transcription factor Lmo4 in thymus development through genetic interaction with Cited2 – Dev. Dyn. (2010) 239, 1988-1994.

 

Stevens J, Ermakov A, Bragança J, Hilton H, Underhill P, Bhattacharya S, Brown NA and Norris DP – Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow – BMC Dev. Biol. (2010) 10, 54.

 

Woon PY#, Kaisaki PJ#, Bragança J, Bihoreau M-T, Levy JC, Farrall M and Gauguier D - Aryl hydrocarbon receptor nuclear translocator-like protein (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes - Proc. Natl. Acad. Sci. USA (2007) 104, 14412-14417.

 

Fox SB, Bragança J, Turley H, Campo L, Han C, Gatter KC, Bhattacharya S and Harris AL - CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia inducible factor 1α - Cancer Res. (2004) 64, 6075–6081.

​

Bamforth SD#, Bragança J#, Farthing CR#, Schneider JE, Broadbent C, Clarke K, Neubauer S, Brown NA, Anderson RH and Bhattacharya S - Cited2 controls left-right patterning and heart development through a Nodal–Pitx2c pathway - Nature Genet. (2004) 36, 1189-1196.

 

Kranc RK, Bamforth SD, Bragança J, Norbury C, van Lohuizen M and Bhattacharya S - Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF - Mol. Cell Biol. (2003) 23, 7658-7666.

​

Bragança J, Eloranta JJ, Bamforth SD, Ibbit JC, Hurst HC and Bhattacharya S - Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2 - J. Biol. Chem.  (2003) 278, 16021-16029.

​

Bragança J, Swingler T,  Marques FIR, Jones T, Eloranta JJ, Hurst HC, Shioda T and Bhattacharya S - Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2 - J. Biol. Chem. (2002)  277, 8559-8565.

 

Yahata T, Takedatsu H, Dunwoodie SL, Bragança J, Swingler T, Hur J, Coser KR, Isselbacher KJ, Bhattacharya S and Shioda T - Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells - Genomics (2002) 80, 601-613.

 

Morin P#, Bragança J#, Bandu M-T, Lin R, Hiscott J, Doly J and Civas A - Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-a gene transcription - J. Mol. Biol. (2002) 316, 1009-1022.

​

Bamforth SD#, Bragança J#, Eloranta JJ, Murdoch JN, Marques FIR, Kranc RK, Farza H, Henderson DJ, Hurst HC and Bhattacharya S -  Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator - Nature Genet. (2001) 29, 469-474.

 

Bragança J and Civas A - Type I interferon gene expression: Differential expression of IFN-A genes induced by viruses and double-stranded RNA - Biochimie  (1998) 80, 673-687.

​

Bragança J, Génin P, Bandu M-T, Darracq N, Vignal M, Cassé C, Doly J and Civas A - Synergism between multiple virus-induced factor-binding elements involved in the differential expression of IFN-A genes - J. Biol. Chem. (1997) 272, 22154-22162.

​

Génin P, Bragança J, Darracq N, Doly J and Civas A - A novel PRDI and TG-binding activity involved in the virus-induced transcription of the IFN-A genes - Nucleic Acids Res. (1995) 23, 5055-5063.